The most loved component of a married couple’s relationship will almost always be their children. A child is always welcomed with love or gladness anywhere in the globe. On the other side, the situation is different when a couple tries frequently but is unsuccessful in conceiving. Doubts begin to surface, which just adds to the overwhelming feeling. As a result, many couples are exploring egg freezing as a safety measure for future for fertility preservation.
Freezing embryos and eggs: what is it?
Dr. Neha Gupta of Mediworld Fertility described egg freezing. Infertility is a medical word that is frequently used to describe couples who have been attempting to conceive for more than a year without success. Even the process of infertility is stressful. Fortunately, there are ways to address the illness thanks to modern breakthroughs. Many occurrences of infertility are caused by issues with the eggs. Egg freezing is a possibility when you are younger and egg production is in a healthy range.
What are the benefits of freezing eggs for women?
Your age significantly affects your chances of becoming pregnant. The likelihood of developing healthy eggs significantly decreases as you age. If you desire to have a kid as you become older, it could be difficult. However, it’s not always possible to have children when you’re young. Some women struggle to find the proper companion, while others put their careers first.
All of this creates a complex situation, therefore freezing eggs is something you should definitely take into account. Eggs that have been frozen do not deteriorate or age. You can use those eggs if you decide to become pregnant in the future. Even without a sexually active male partner, you can achieve that. Donor sperm is even useful for that purpose.
In addition to age, you should think about the possibility of a future illness or medical condition that could lead to infertility. For instance, it is well known that cancer therapies have an impact on the ovaries and harm the eggs, resulting in an early menopause. Choosing to store her eggs before starting cancer treatment is an option for women.
Another possibility during IVF operations is egg freezing. For future IVF cycles, women can opt egg freezing. If an IVF cycle fails, this may be useful.
Process of Egg Freezing
The chief infertility and IVF specialist at Mediworld Fertility in Delhi Dr. Neha Gupta, described egg freezing as a technique that involves the preservation of the woman’s eggs. These eggs are taken straight from women’s ovaries. They are kept in storage so that they might be used later.
The eggs are thawed and then mixed with sperm if the woman decides to use them in the future. In order to facilitate pregnancy, the fertilised eggs are then inserted into the uterus of the woman or even a carrier female. The degradation of germ cells is the primary cause of infertility issues, but the uterus is still fully functional. Eggs can be frozen under these circumstances, which is quite beneficial.
Preserving and extending fertility
For older women, getting pregnant might be challenging because of things like late marriage and health issues. One of the finest ways to maintain your youthful reproductive potential is to freeze your eggs. Fertility extension and preservation are the two main justifications for freezing eggs.
Fertility preservation: This medical procedure tries to protect women’s ability to procreate. It is especially utilised when an illness or a disease-related treatment has a risk of impairing fertility. These conditions consist of.
Treatments for cancer that directly affect fertility include chemotherapy and pelvic radiation. The most prevalent form of cancer among women is breast cancer. Leukemia, cervical cancer, colon cancer, and lymphoma are a few other common health worries. Chemotherapy is frequently required for women as part of their treatment, regardless of the type of cancer they have. The quantity of eggs in the ovary is known to decrease after exposure to chemotherapy. Even premature ovarian failure is a possibility.
Chemotherapy may also be necessary as part of the treatment for other autoimmune illnesses. These include lupus nephritis, which needs cyclophosphamide as a therapy.
Bone marrow transplantation may also be necessary in the treatment of some benign disorders including sickle cell disease and aplastic anaemia. which downplay the possibility of early ovarian failure.
Both ovaries may need to be removed in order to prevent malignancy. This results in an early menopause.
Women who have genetic conditions including Turner syndrome and fragile X premutation may have premature menopause. Premature menopause can also result from ovarian operations and family history.
Fertility Extension: This situation occurs when a woman decides to maintain her reproductive potential in order to put off having children. It could be due to social, professional, or even personal circumstances. In any case, female fertility preservation can prolong the period of natural fertility.
The procedure involves
Ovarian Stimulation: At this stage, fertility drugs are used to stimulate the ovaries. Age and ovarian reserve have an impact on how the ovaries react and how many eggs they generate. In the event that a woman is identified as having an estrogen-sensitive malignancy, such as breast cancer, the technique of ovarian stimulation may need to be changed. The stimulation is finished after about two weeks.
Egg retrieval: Once the eggs are laid, they must be recovered in order to be preserved. The egg retrieval technique is carried out as an outpatient under anaesthesia. With the aid of a needle that is inserted through the vagina, the eggs are harvested. After the eggs have been recovered, they are checked to see whether or not they are mature. Many institutions only freeze the fully developed eggs. Some facilities may even use an in vitro maturation technique to develop the egg before freezing it.
Freezing: After retrieving and checking the eggs for 4-5 hours, they are frozen. Either slow freezing or quick freezing techniques are applied for this. In both situations, a man-made chemical known as a cryoprotectant is utilised to lessen the production of ice crystals that could harm the oocyte.
H4 Methods of Egg Freezing
Two techniques for freezing eggs were described by Dr.Neha Gupta of Mediworld Fertility in Delhi, a laparoscopy and IVF specialist.
Slow freezing: With this technique, low amounts of the cryoprotectant are utilised. The eggs are put in a vial with the cryoprotectant, and a programmable freezer is used to gradually freeze the eggs.
Vitrification: The eggs are placed on a special apparatus and are frozen using high quantities of cryoprotectant. For lowering the temperature to -196 degrees Celsius, liquid nitrogen is employed. The tool that is most frequently used for vitrification is the cryotop. The contraption resembles a straw with a cap and a narrow strip for holding the eggs.
Risks associated with the procedure
You should be aware of any potential dangers involved with the operation before you proceed. Typical dangers include:
There is, first and foremost, no assurance that the surgery will unquestionably be successful. You must be emotionally prepared for the situation and not rely on unfounded optimism. The procedure still carries some dangers even though it can be an empowering and constructive move for you.
You are given fertility medications right at the start of the surgery. These medications have the potential to lead to specific medical issues. Fertility medications, which are frequently administered intravenously, might result in mild nausea, bloating, and abdominal pain. Even ovarian hyperstimulation syndrome is a possibility. Rarely, the fluids may build up and result in breathlessness as well.
The egg retrieval technique may have complications. The eggs are removed using needles, which increases the risk of bleeding and infections of the bladder, bowel, and blood vessels.
Preparing for the process of Embryo Freezing
Making the decision to freeze your eggs is not simple. There are numerous factors to take into account. You should also take other options like freezing embryos into account. You need sperm in addition to your egg as the embryo is simply the fertilised egg. A sperm donor can be employed if a male partner is not available. Of course, freezing the eggs is always a possibility if the lady refuses to use sperm at all.
You will need to go through a number of examinations and screening procedures prior to the surgery starting. Ovarian reserve testing is frequently done by medical professionals to evaluate the quantity and quality of your eggs. The test’s results are useful in predicting how the ovaries will react to the fertility medications. There will also be screening exams for various disorders, like HIV. You are ready to go once every test has been completed. Of course, you can consult your doctor if you are unsure.
Egg Freezing Success Rates
Egg Freezing Success Rate: According to Dr. Neha Gupta, Senior Consultant & IVF Specialist at Mediworld Fertility, Faridabad “You would want to know your chances of success as 100% success is not guaranteed. You should be aware of both the overall success rate and the success rate of the particular IVF centre you are visiting before you decide to freeze your eggs.
There are a few variables at play here. First of all, egg freezing is a very recent technological advancement. This indicates that there is a dearth of information on children born following egg thawing. Additionally, the information that is given may not necessarily apply to your particular nation. Even the existence of birth abnormalities in children born following egg freezing is not sufficiently known. It is challenging to evaluate the success rates of the method for egg freezing in the absence of long-term data.
The most important information, from a woman’s perspective, relates to successful pregnancies and live births that have been produced following egg thawing. The ability of the frozen eggs to give birth to a child intrigues all women. It describes how an egg bounces back after thawing and develops into an embryo. Given that miscarriages are common among older women, they must also be taken into account.
In conclusion, storing eggs is a fantastic way for women to maintain their fertility. There are things to think about, and you should conduct the required independent investigation. You must determine whether using the option is appropriate for you. Before making a choice, you should consider the procedure’s advantages and disadvantages.