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Needle-Free IVF Injections in Delhi

August 6, 2026
5 min read

Looking for needle-free IVF in Delhi NCR? Mediworld Fertility offers the Needle-Free Injection System (N-FIS) at its centres in Delhi, Faridabad, Ghaziabad, and Greater Noida. Led by Dr. Neha Gupta, our team provides personalised IVF treatment with a more comfortable, needle-free injection option for eligible patients under expert medical supervision.

Key Takeaways

  • Needle-Free Injection System (N-FIS) delivers IVF hormone medicines through the skin using a high-pressure jet with no needle required.
  • N-FIS for IVF in India is now available through a partnership between Intas Pharmaceuticals and IntegriMedical, a Pune-based healthcare company.
  • Since its retail launch in April 2024, N-FIS has been used in over 50,000 administrations by more than 1,100 doctors across 25 states and 180 cities in India.
  • Early clinical studies show needle-free injection systems produce successful ovarian stimulation and are associated with minimal pain and high patient satisfaction.
  • Mediworld Fertility now offers N-FIS as part of its IVF treatment options at its Delhi NCR centres.

Needle-Free IVF infographic showing how the N-FIS device delivers IVF hormone medication without needles, reducing pain and injection anxiety while supporting ovarian stimulation at Mediworld Fertility Delhi NCR.

Are You Scared of IVF Injections? You Are Not Alone

If the thought of daily IVF injections makes you feel anxious, you are not alone. Across India, fear of needles is one of the most common reasons couples delay starting their IVF journey even when they strongly want a child.

Why so many people fear IVF injections

A standard IVF cycle involves hormone injections given daily for around 10 to 14 days to stimulate the ovaries to produce eggs. These injections are given under the skin, usually in the abdomen. While the needles used are thin, the idea of injecting yourself every single day often while managing work, emotions, and family creates a level of anxiety that many people find very hard to manage.

How injection fear stops couples from starting IVF

Doctors at Mediworld Fertility regularly speak with couples who say they are ready to try IVF but are putting it off because of the injections. This delay can have real consequences. India currently sees an estimated 300,000 to 350,000 IVF cycles per year, with projections suggesting this could rise to 500,000 to 600,000 cycles annually by 2027. Behind those numbers are hundreds of thousands of women going through multiple daily injections and many more who are not starting because of injection-related fear.

Is there a way to do IVF without painful injections?

A technology called the Needle-Free Injection System (N-FIS) now offers a real alternative. It delivers the same IVF medicines into the body without using a traditional needle. Mediworld Fertility has made this option available at its Delhi NCR centres, giving patients in Delhi, Faridabad, Ghaziabad, and Greater Noida access to a more comfortable IVF experience.

Introducing Needle-Free IVF A New Way to Do IVF Without Pain

What is the Needle-Free Injection System (N-FIS)?

The Needle-Free Injection System, or N-FIS, is a medical device that delivers medicines through the skin using a fine, high-pressure jet of liquid instead of a needle. The medicine passes through the skin in less than a tenth of a second. There is no puncture, no sharp point, and no metal entering the body.

In India, N-FIS has been developed and manufactured by IntegriMedical, a Pune-based healthcare startup. Intas Pharmaceuticals, one of India’s major pharmaceutical companies, has secured exclusive rights to offer N-FIS specifically for IVF and gynaecology treatments across the country.

How is this different from traditional IVF injections?

In a standard IVF cycle, a patient uses a small syringe with a fine needle to inject hormones under the skin each day. Even though the needles are thin, repeated daily injections can cause discomfort, bruising, and growing anxiety over time. N-FIS removes the needle entirely. The medicine is loaded into the device, which is pressed gently against the skin. A precisely controlled jet delivers the medicine instantly. The sensation is described as a quick pressure, not a sharp sting.

Is painless IVF treatment really possible?

Early research supports this. A pilot study published in the journal Fertility and Sterility evaluated the use of a needle-free injection system for administering gonadotropins (the hormone medicines used in IVF) in 20 patients undergoing controlled ovarian stimulation. The study found that the technique was associated with minimal pain and a high patient satisfaction rate, with successful ovarian stimulation achieved in patients who completed the trial. The researchers noted that larger studies would be needed to confirm these findings at scale and that research is now ongoing.

How Does Needle-Free IVF Work?

The science behind needle-free injection technology

N-FIS works on a well-established principle: when a liquid is pushed through a very small opening at high speed, it can penetrate the skin without a needle. The pressure is calculated precisely so the medicine is deposited exactly where it needs to go under the skin in a consistent, predictable pattern.

How high-pressure jet delivery works without a needle

The device contains a spring or gas-powered mechanism. When activated, it pushes the medicine through a tiny opening at high speed. The jet is so fine that it passes through the outer layer of skin and deposits the medicine in the tissue below in a fraction of a second. According to IntegriMedical, the mechanism delivers medication in less than a tenth of a second. Unlike a needle injection, N-FIS avoids tissue trauma, prevents medication pooling, and reduces the risk of cross-contamination.

Is it safe for fertility treatments like IVF?

The medicines used in IVF such as gonadotropins for ovarian stimulation are the same whether given by needle or by N-FIS. Only the delivery method changes. N-FIS meets international standards for needle-free injection systems, including ISO 21649:2023, which sets requirements and test methods for single-use and multiple-use needle-free injection systems for medical use. The device used in India by IntegriMedical also holds CDCO approval (Central Drugs Standard Control Organisation) and meets MDSAP (Medical Device Single Audit Program) standards.

Does Needle-Free IVF Give the Same Results?

This is the most important question for any patient considering N-FIS. The early evidence is encouraging.

What clinical research says about N-FIS in IVF

A pilot study in Fertility and Sterility tested the J-Tip Needle-Free Injection System in 20 IVF patients receiving hormone injections for ovarian stimulation. The primary outcome measured was the number of eggs collected per patient. The study found the system achieved successful ovarian stimulation and pregnancies were achieved in the study, with patients reporting high overall satisfaction. The researchers noted that larger, multicentre studies are still required to fully compare N-FIS against standard needle injections at scale. This means the technology is promising and clinically supported at the early research level, while broader evidence continues to develop.

What Cloudnine and other leading Indian clinics report

Cloudnine, one of India’s largest maternity and fertility hospital chains, has integrated N-FIS into its fertility treatment protocols. According to Cloudnine, needle-free systems have been found to deliver medication effectively and safely, with results comparable to traditional injections. The system’s accuracy supports the precise hormonal balance needed for follicle maturation, while also reducing bruising and injection site pain particularly important for patients taking multiple doses every day.

What the IVF medicines landscape looks like in India

Intas Pharmaceuticals, which now holds exclusive rights to distribute N-FIS for IVF in India, has stated that at the scale of India’s IVF market, the technology could positively impact the treatment experience for hundreds of thousands of women annually. This is significant in a market that currently sees several million individual IVF injections administered every year.

How Much Pain Will You Feel?

IVF injection: how much does it actually hurt?

Traditional IVF injections are given with fine needles and are not extremely painful individually. The challenge is repetition. Doing 10 to 14 injections over two weeks, while also managing emotional stress, means that bruising, skin sensitivity, and anxiety tend to build up. Many patients say the injections themselves are manageable but the daily ritual of preparing and giving an injection is what wears them down.

What needle-free injection feels like

According to published patient feedback from clinical use of N-FIS, the sensation from a needle-free injection is typically described as a quick pressure or a light snap against the skin, rather than the sharp, penetrating feeling of a needle. The absence of a visible needle also significantly reduces the psychological stress associated with injecting.

How N-FIS reduces fear and anxiety around injections

Fear of needles is not just physical, it is also mental. Preparing a syringe, seeing the needle, and pressing it against your own skin are actions that trigger anxiety even before any physical sensation. N-FIS changes this experience. With no needle involved, the mental preparation is much lighter, and patients feel more in control of the process.

Who Should Consider Needle-Free IVF?

N-FIS is not only for people with severe needle phobia. It may be a better option for a wider group of patients.

People with needle phobia or injection anxiety

If you have avoided medical procedures because of needles, or feel faint, anxious, or distressed around needles, N-FIS is specifically designed to address this. You do not need to push through extreme discomfort to pursue IVF treatment.

Patients who have had a difficult IVF cycle before

If you have completed IVF in the past and found the daily injections to be the most difficult part of the experience, N-FIS gives you the option of a more comfortable approach in your next cycle.

First-time IVF patients

For first-time patients, starting IVF is already emotionally loaded. Removing the needle from the daily injection process reduces one significant source of stress before treatment even begins.

Is Needle-Free IVF Certified and Safe?

CDCO and MDSAP approval what it means for you

The N-FIS device used in India is approved by the Central Drugs Standard Control Organisation (CDCO), India’s national regulatory authority for medical devices. It also meets the Medical Device Single Audit Program (MDSAP) standards, which are recognized by regulatory bodies in the USA, Canada, Australia, Brazil, and Japan. These approvals mean the device has been independently assessed and verified for safety and performance.

ISO 21649:2023 the international standard for needle-free systems

Needle-free injection systems used in medical settings are governed by ISO 21649:2023, an international standard that sets out specific requirements and test methods for single-use and multiple-use devices. This standard applies to N-FIS devices used in clinical and personal settings, including fertility treatment.

How Mediworld Fertility ensures safety in every injection

At Mediworld Fertility, N-FIS is offered as part of a structured, medically supervised treatment plan. Every session is guided by the clinical team. The medicines used remain the same as in a traditional IVF cycle only the delivery device changes. Patients considering N-FIS discuss their suitability with their doctor before the cycle begins.

Why Delhi Patients Are Choosing Mediworld Fertility for Needle-Free IVF

N-FIS is now available at Mediworld Fertility centres in Delhi NCR

Mediworld Fertility has introduced N-FIS as a treatment option across its network of centres in Delhi NCR. This includes locations in Safdarjung Enclave, Sukhdev Vihar, Faridabad, Ghaziabad, and Greater Noida covering a wide area of the NCR for patients who prefer to avoid traditional needle injections during their IVF cycle.

An experienced team you can trust

Mediworld Fertility is led by Dr. Neha Gupta, Clinical Director and Senior IVF Specialist with 21 years of experience in reproductive medicine, who has guided over 2,000 couples through fertility treatment. The team also includes Dr. Sushma Ved, Director and Senior Consultant in Embryology with 22 years of experience and over 6,000 procedures performed. The fertility team works together to build personalised treatment plans including the choice of N-FIS where appropriate.

What makes Mediworld Fertility a trusted choice in Delhi NCR

Mediworld Fertility has been treating infertility since 2018. The Safdarjung Enclave centre holds NABH accreditation, reflecting its commitment to clinical quality and patient safety. The clinic offers a full range of fertility treatments including IVF, IUI, ICSI, cryopreservation, donor programmes, surrogacy, and now N-FIS all under one roof.

Bina suyi ke IVF ab Delhi NCR mein available hai

Agar aap Delhi, Faridabad, Ghaziabad, ya Greater Noida mein rehte hain aur IVF ke injections se darte hain, toh Mediworld Fertility mein needle-free IVF ka option ab uplabdh hai. Apne doctor se baat karein aur jaanein ki kya N-FIS aapke liye sahi hai.

What to Expect at Mediworld Fertility Your First Visit

Step-by-step: how needle-free IVF works at Mediworld Fertility

  1. Book a consultation with a Mediworld Fertility specialist at your nearest centre
  2. Discuss your fertility history, previous treatments, and any concerns about injections
  3. Complete initial blood tests and ultrasound evaluation
  4. Receive a personalised treatment plan your doctor will advise whether N-FIS is suitable for you
  5. Begin your IVF stimulation cycle using N-FIS under medical supervision
  6. Attend monitoring appointments to track follicle development via ultrasound
  7. Proceed to egg retrieval and embryo transfer as per your treatment plan

How to reach Mediworld Fertility

You can contact Mediworld Fertility in three ways:

  • Call: +91 9315615376
  • WhatsApp: +91 7048990753
  • Visit: Aashlok Hospital, 25-AB Safdarjung Enclave, New Delhi 110029 (or any NCR centre in Sukhdev Vihar, Faridabad, Ghaziabad, or Greater Noida)

What to ask your doctor about N-FIS

When you visit, consider asking your doctor:

  • Am I a suitable candidate for N-FIS based on my medical history?
  • Will my IVF medicines work equally well when given through N-FIS?
  • Are there any situations in my cycle where a traditional injection might still be needed?
  • What does the N-FIS experience feel like compared to a regular injection?

Take the First Step Towards a More Comfortable IVF Journey

Fear of injections should not stand between you and your dream of becoming a parent. With the Needle-Free Injection System now available at Mediworld Fertility in Delhi NCR, there is a clinically supported alternative to traditional IVF injections one that puts patient comfort at the centre of your treatment.

Whether you are in Delhi, Faridabad, Ghaziabad, or Greater Noida, Mediworld Fertility has a centre near you. Our team, led by Dr. Neha Gupta, is here to guide you from your very first consultation through every step of your fertility journey.

Book your consultation today. Call +91 9315615376 or WhatsApp us at +91 7048990753.

Frequently Asked Questions

Is needle-free IVF available in India? expand_more

Yes. N-FIS for IVF is now available in India through Intas Pharmaceuticals in partnership with IntegriMedical. Since its retail launch in April 2024, the device has been used in over 50,000 administrations by more than 1,100 doctors across 25 states and 180 cities. Mediworld Fertility offers this option at its Delhi NCR centres.

Is N-FIS as effective as regular IVF injections? expand_more

Early clinical research shows that needle-free injection systems can successfully support ovarian stimulation in IVF, with patients reporting high satisfaction. Larger comparative studies are still underway. Your doctor at Mediworld Fertility can discuss the current evidence with you and help you decide whether N-FIS is the right choice for your specific treatment.

How to reduce IVF injection pain? expand_more

The most direct solution for reducing IVF injection pain is N-FIS, which removes the needle entirely. Other practical steps include applying a cold compress briefly before injection, rotating injection sites to avoid skin sensitivity, and keeping the injection area relaxed. Speak with your Mediworld Fertility nurse or doctor about what combination of approaches works best for you.

Which is the best IVF clinic in Delhi NCR for needle-free IVF? expand_more

Mediworld Fertility offers N-FIS as part of its IVF treatment at multiple Delhi NCR locations. With NABH accreditation, an experienced clinical team, and centres across Delhi, Faridabad, Ghaziabad, and Greater Noida, it is a well-established choice for patients looking for advanced fertility care in the region.

IVF without injections is N-FIS completely needle-free? expand_more

N-FIS makes the daily hormone stimulation injections needle-free. Other parts of IVF such as blood tests for monitoring and the egg retrieval procedure itself (which is done under sedation) still involve standard medical procedures. The stimulation phase, however, is where most of the frequent daily injections occur, so N-FIS addresses the part of IVF that patients typically find most difficult.

What is the needle-free IVF injection price in India? expand_more

The cost of adding N-FIS to an IVF cycle at Mediworld Fertility depends on your individual treatment plan. For a transparent cost breakdown, speak with the Mediworld Fertility team during your consultation. Call +91 9315615376 or WhatsApp +91 7048990753 to get started.

What size needle is used in traditional IVF injections? expand_more

Standard IVF hormone injections use a fine subcutaneous needle, typically around 27 to 30 gauge in size (the higher the gauge number, the thinner the needle). While these are among the thinnest needles available, the daily repetition over 10 to 14 days is what causes cumulative discomfort and anxiety for many patients. N-FIS removes the needle entirely from this part of the process.

's Medical Content Team

Dr. Neha Gupta's Medical Content Team

Dr. Neha Gupta’s medical content team specialises in creating accurate, clear, and patient-focused healthcare content. With strong clinical understanding and expertise in technical writing and SEO, the team translates complex medical information into reliable, accessible resources that support informed decisions and uphold Dr. Neha Gupta’s commitment to quality care.

This content is reviewed by

Dr. Neha Gupta

Clinical Director & Sr. Consultant (IVF Specialist)

Dr. Neha Gupta is a senior IVF and fertility specialist in Delhi, currently serving as Director and Senior Consultant at Mediworld Fertility, Aashlok Hospital.

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